3/22/2010- Pam struggled with constant abdominal pain, lack of appetite, lack of energy and dwindling hope for feeling better. None of her medications worked as planned, even after new pain medications were prescribed. We expect the hear the results of the last biopsy this week. Other tissue specimens will be submitted to Moffitt and the Mayo Clinic in advance of our appointments in April. These events will be a measure of progress toward seeking an alternative treatment to the chemotherapy, especially in view of the seemingly long period of time to hear about the biopsy.

Pam had a period of time todaywith no pain and awoke from a nap well refreshed. Although pain patches were prescribed today, she had not applied one before her nap. I believe Pam's outlook for relief has been refreshed.

Please bear in mind that all your prayers and support have helped us endure the effects of this cancer and give us encouragement for daily living.

March 14, 2010 This week has just flown by. Pam has been blessed with visits by friends she has had for more than 15 years. Traditionally, Pam and three friends try to meet at least annually for fun and fellowship. This year Sally and her husband Dan from the Atlanta area took time on their anniversary trip to spend two nights here. Later in the week, Ann and Bennie flew in from Dallas and New Orleans, respectively, to spend nearly three days of just "hanging out." Time was spent at the beach, at the restaurant, at the concert, and just doing nothing other than being together and having a grand time. Pam says everyone is so comfortable with each other that they just pick up where they left off, no matter how long it has been since they've been together. Of course, Pam had a wonderful experience although she is very tired. Above all, she is very happy and thankful for devoted friends from the past.

Pam has an appointment with a GI oncologist at the Moffitt Cancer Center in Tampa scheduled for April 8th. Before that date was confirmed, we arranged a visit to the Mayo Clinic in Jacksonville to seek a treatment plan for April 8th. We will sort out this scheduling dilemma this week.

Thank you for your prayers and unfailing support as we look for the next step in dealing with the cancer and its effects.

3-5-2010 Pam met with a Moffitt Cancer Center physician in the GYN clinic in a followup to her May 2009 visit. In comparing pathology reports from June 2009 and February 2010, we learned that the reports focused more on cancer cells in the bile duct in the liver than cancer cells in the ovaries. In view of all the chemotherapy treatments with no consistent measurable results, the doctor believes that a diagnosis of cancer of unknown primary is appropriate. Pam will be referred to a medical oncologist in the Moffitt GI Department for review and evaluation of GI tract adenocarcinomas and possible diagnosis of cholangiocarcinoma (bile duct cancer). We were unable to speak to any member of the medical staff in the GI Department or anyone familiar with phase I clinical trials.

The visit to Moffitt did not meet our expectations,, but we must now be more assertive and diligent in seeking test results and comparative analyses.

Your prayers and blessings have brought us comfort and hope. We remain optimistic for a treatment that will make Pam more comfortable.